|
KMID : 0360220210620040479
|
|
Journal of the Korean Ophthalmological Society
2021 Volume.62 No. 4 p.479 ~ p.488
|
|
|
Five-year Change in Corneal Endothelial Cell Density after Foldable Iris-fixed Lens Insertion
|
|
Nam Myung-Sik
kang Sung-Yong
Kim Sun-Woong
|
|
|
Abstract
|
|
|
Purpose: To investigate changes in corneal endothelial cell density over 5 years after implantation of Artiflex lenses (Ophtec BV,Groningen, The Netherlands) and to explore the influence of anterior chamber depth and volume on changes in endothelial celldensity.
Methods: This study included 146 eyes of 88 patients implanted with foldable phakic iris-fixation intraocular (Artiflex) lenses formyopia correction from March 2009 to March 2014. To simulate chronological changes in endothelial cell density with age, wecollected normal endothelial cell density data from 100 healthy subjects aged 20, 25, or 30 years, and compared the changesamong these groups at 5 years after surgery. Changes in corneal endothelial cell density were compared among four groups towhich subjects were assigned based on the distance from the intraocular lens to the corneal endothelium, and the volume anddepth of the preoperative anterior chamber.
Results: The mean endothelial cell density, pre-operatively and at 1, 3, and 5 years post-operatively, was 3,038.8 ± 223.2,2,985.3 ± 235.5, 2,905.1 ± 231.3, and 2,814.9 ± 250.5 cells/mm2, respectively (1.73%, 4.36%, and 7.31% reduction, respectively,vs. pre-operatively, p < 0.001). These differences were greater than those observed among different age groups(2.2% difference between 20- and 25-year-olds, and 1.2% difference between 25- and 30-year-olds, p < 0.001). A shorter distancefrom the lens to the endothelium and smaller anterior chamber volume were associated with greater decreases in endothelialcell density following surgery.
Conclusions: Corneal endothelial cell density significantly decreased during a 5-year follow-up after Artiflex lens implantation. The distance from the intraocular lens to the corneal endothelium, and the anterior chamber volume, were negatively correlatedwith the rate at which endothelial cell density decreased over time.
|
|
|
KEYWORD
|
|
|
Anterior chamber, Corneal endothelial cell loss, Phakic intraocular lenses
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|